Advancement in the exploration of the human brain
We are proud to present a long-term work on the 3D reconstruction of large specimens from the human brain cortex just published by Biomedical Optics Express Vol. 12, Issue 6, pp. 3684-3699 (2021) https://doi.org/10.1364/BOE.415555
See also the 2020 preprint at: https://www.biorxiv.org/content/10.1101/2020.08.06.219444v2 with more details on the 2.5D reconstruction approach developed by Bioretics.
The 3D analysis of the human brain architecture at cellular resolution is still a big challenge. In this work, we propose a pipeline that solves the problem of performing neuronal mapping in large human brain samples at micrometer resolution.